Veterinary Systemic Antibacterial
Active ingredient of Tilcova Injectable Solution is Tilmicosin. Tilmicosin is an antibiotic in macrolide group which has generally spectrum of gram-positive bacteria. It indicates effect on bacteria by inhibiting protein synthesis as with other macrolide. The peak plasma concentration obtained within 1 h in serum, remains 0.07 mg / mL level for 3 days, after injection of a single dose that is 10 mg / kg body weight to hypodermic. Tilmicosin bactericidal effective concentration in lung tissue is 60 times higher than the plasma concentration of serum, for 3 days protects the tissue level. This feature creates a preference option in the treatment of respiratory tract infections.
Tilmicosin is preferred option in the treatment of the following infections:
Staphylococcus aureus, Staphylococcus agalactia, Pasteurella haemolytica, P. Multocida, Haemophilius somnus, Fusobacterium necrophorum, Mycoplasma dispar, M.bovirhinis ve M.bovoculi.
A small amount of medicament have a biotransformation in liver, becomes the main metabolite of N-desmethyl tilmicos (T1) and the small amount of T2 and T3.
If not otherwise recommended by veterinarians;
Pharmacological doses: 10mg/kg are injected subcutaneously as a single dose.
Practical doses: 1 ml/30 kg
If the drug is given more than 15 ml, it should be injected in two different regions.